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. This project will use large-scale metagenomic mining to uncover novel phage-host associations and identify phage-encoded enzymes, such as endolysins, with antibacterial activity. By integrating evolutionary
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Abstract: Medical device-associated infections (MDAIs) are a major clinical and economic burden, particularly in orthopaedics where implant-related infections can lead to severe complications, including
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Supervisors: Dr. Michele Crotti Dr. Martyna Michalska Abstract: Biofilm-associated infections account for nearly 80% of human microbial infections and are notoriously resistant to antibiotics and
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, reduce the need for systemic antibiotics, and mitigate the development of AMR in oral pathogens. The approach may also be extended to other biomedical applications involving biofilm-associated infections