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initiative investigating how human-specific features of brain development shape early behavior and neural circuit function in autism spectrum disorders (ASD). This position is a joint effort between the
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mechanisms involving genetic, epigenetic and chromatin organisation factors governing the cell-type specific response to ARS mutations. Therefore, integrative genome-wide cis-regulatory network analysis
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results. Strong interest in immunology and neurodegeneration; experience with human samples and/or immunophenotyping tools is a plus (eg flow cytometry) Comfortable working at the clinic–lab interface
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murine microenvironments and use high-resolution spatial omics techniques to prioritize molecular factors that may drive the immune cell states. These will then be validated through in vivo screening
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data. We have developed in vivo single-cell CRISPR technologies to screen for dozens of molecular factors in vivo during developmental and disease. These technologies are a game-changer in the speed
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neuroinflammation. The PhD student will help uncover the molecular and cellular pathways linking the allergic gut to the inflamed brain, and how these pathways shape disease risk later in life. The successful
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that you can help to shape. Position You will work actively on the preparation and defence of a PhD thesis in the field of neuroimmunology You will publish scientific articles related to the research
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, including animal studies and analyses of human tissue samples. This full-stack methodology enables us to directly link molecular channel function with disease phenotypes. The PhD student will work under the
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for Medical Biotechnology focuses on the development of new and innovative molecular tools and technologies to address human health problems. The center translates its insights to widely applicable research