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plasticity at the atomic level. At the center of this regulation lies PGC-1α, a transcriptional co-activator and master regulator of metabolic processes. PGC-1α dysfunction has been linked to obesity, diabetes
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demonstrating how an existing anti-biofilm compound binds to and activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity
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cancer; see https://data.snf.ch/grants/grant/189065 Design, development and implementation of multi-step synthesis to access small heterocyclic molecules. Improve biological activity of hit compounds
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activates its specific target in Pseudomonas aeruginosa, we will design, develop and test novel anti-biofilm compounds with broader activity against the WHO priority pathogens Escherichia coli, Klebsiella
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their own research questions. They are expected to collaborate closely with other team members and researchers from other institutions, will co-supervise PhD and MSc students, and contribute to teaching and
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with diverse interdisciplinary collaborations and international networks. Many of our activities focus on a common interest in European history in a global perspective. With the Center for African