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competitive selection (SELEX), starting from artificial libraries of large numbers (~10^15) of distinct sequences. When the experiment succeeds, variants that perform the selected function well are enriched
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coordinated mechanisms, which include DNA Damage Response (DDR), the control of cellular proliferation or apoptosis induction. IR exposure might lead to genomic instability, chromosomal aberrations and cancer
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Postdoctoral position: Developing a human lymphoid organ-on-chip to evaluate candidate mRNA vaccines
. To address this issue, we developed a lymphoid organ-on-chip (LO chip) model based on a microfluidic chip seeded with human PBMC at high density within a 3D matrix. Perfusion of the SARS-CoV-2 Spike
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increase in the number of strains that are multi-resistant to antifungal agents is leading to a growing incidence of two other species, C. glabrata and C. auris. Being a complex and dynamic structure
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(11). Theunissen FE and Elie JE, Neural processing of natural sounds. Nat Rev Neurosci, 2014. 15(6): p. 355-66. Yizhar O., et al., Optogenetics in neural systems. Neuron, 2011. 71(1): p. 9-34
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. Measuring and predicting the effect of copy number variants on general intelligence in community-based samples. JAMA Psychiatry 2018 75(5):447-457. –Bourgeron T. From the genetic architecture to synaptic
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. Measuring and predicting the effect of copy number variants on general intelligence in community-based samples. JAMA Psychiatry 2018 75(5):447-457. Mercati O. et al. CNTN6 mutations are risk factors for