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project focused on dissecting how the various cellular tasks of MYC are orchestrated in individual cells. You will integrate loss- and gain-of-function tools (e.g., CRISPR/Cas and degron systems) with a
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therapeutic targets. Recent relevant publications: Clarke, B., Holtkamp, E. et al. Integration of variant annotations using deep set networks boosts rare variant association testing. Nature Genetics 56, 2271
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the genetic etiology and developing diagnostics and treatment methods for these diseases. Approaches range from human genetics, genomics, protein biochemistry and neuronal and glial cell biology to integrative
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of Pediatric Immunology and Rheumatology at the University Hospital of Bonn and Principal Investigator of an ERC Consolidator grant (iDysChart), integrating basic research into mechanism of the immune