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wet- and dry-lab scientists that are studying RNA, chromatin and transposon biology, covering all aspects of this RNA-based immune system, including the biogenesis of small non-coding RNAs and the
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automated feeders), and analyse microbiome composition using 16S rRNA and whole-genome sequencing. Statistical modelling will test for links between microbes and host development and fitness.� PROJECT
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processes associated with CIN [1], leveraging single-cell DNA sequencing understand CIN heterogeneity [2], and development and implementation of machine learning and AI models to imaging data [3]. The student
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mouse models and immunology expertise (CRUK-CI), access to relevant patient material (matched fresh-frozen PDAC and serum samples). We will utilize AstraZeneca expertise in spatial and circulatory
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Department/Location: Yusuf Hamied Department of Chemistry Applications are invited for a 4-year PhD studentship based in the Department of Chemistry, University of Cambridge and the new AstraZeneca
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on cell viability and DDR activation in established human cell models. The student will perform CRISPR screens to determine factors that affect resistance/sensitivity and follow these up with mechanistic
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of the genome. This position will be primarily based in the Balasubramanian Lab in the CRUK Cambridge Institute (CRUK CI), and will involve collaborative interactions with the group's sister lab in the Yusuf
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adoption in practice. The project aims to generate a robust scientific evidence base to inform updates to design and specification guidance, with a particular focus on re-evaluating the cement contents
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to elucidate their role, their interactions with proteins and explore small molecule-based intervention strategies for cancer [e.g. see Genome Biology, 2025, 25, 155; Nature Chemistry, 2025, 17, 875; PNAS, 2024
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The PhD studentship will be based at the University of Cambridge in the Department of Materials Science and Metallurgy as part of the Structural Materials Group. The Structural Materials Group is a