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epidemiology, innovative sequencing and bioinformatics technologies including single cell and spatial transcriptomics, molecular biology approaches using cell-based and animal models, and biomarker studies from
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beta-cells, aiming to identify therapeutic targets for beta-cell regeneration in diabetes. Work with mouse and human cells, mouse models, and stem cells in the context of diabetes, utilizing techniques
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research project to develop a neoantigen-based cancer vaccines to support an IND utilizing a highly efficient and fully synthetic poxvirus-vectored vaccine platform that has been derisked by its use in Phase
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utilizes genetic mouse models, molecular biology, imaging and epigenetic techniques to study the cellular identity, function, remodeling, and survival of beta-cells in physiological and pathological
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. The project involves both in vitro and in vivo studies to uncover the molecular and cellular mechanisms driving cancer-associated immunosuppression using mouse and human solid tumor models. Additionally
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or protein structural data analysis is highly preferred. Background with pharmacology, cell therapy or antibody engineering is also desired. · Previous experience in working with animal models
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, glioblastomas, colon cancer, and lung cancer. Advancing precision oncology through machine-learning models: We integrate multimodal patient data, including multiomic data and health record information, to develop
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molecular techniques, genomic approaches, and genetic and xenograft mouse models. For more information on the research lab please visit here . As a successful candidate you will: · Design and conduct
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, and extensive murine studies. · Experience in immunology is an advantage. City of Hope employees pay is based on the following criteria: work experience, qualifications, and work location. City
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following things we are working on this may be the perfect opportunity: 1. Development of cell-free DNA (mutation and methylation), RNA, and exosomal-based liquid assays for early cancer detection, prognosis