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consequences of mitochondrial dysfunction in patients with inherited disorders and in animal models of mitochondrial pathology. The goal is to uncover novel insights into the role of mitochondria in human
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photoreceptive pathways using mouse as a model system. Methods used in the lab include various in vitro, ex vivo and in vivo approaches, as well as functional and behavioral studies of relevant opsin knockout mice
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systems, or network analysis. Experience with methods for causal inference, or modelling of biological systems is also considered a merit, along with prior work involving large-scale sequencing data such as
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in mammals. The Simon lab's primary salamander model is the Iberian newt which has the widest spectrum of regeneration capacity among vertebrates. The lab has established several experimental paradigms
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diseases, including genetics, epidemiology, immunology and epigenetics, with excellent clinical cohorts and experimental models. The Applied Immunology & Immunotherapy group is physically located
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transcriptomics and genomics datasets. The goal is to identify molecular and spatial signatures of disease progression both in human samples and in experimental models of diabetes. Qualifications: PhD in
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bioinformatics, with a particular emphasis on performing analysis of high-dimensional data, which can be sequencing and/or imaging-based. Experience working with AI and machine learning approaches are considered a
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., Nature Cell Biology, 2018). The Teixeira lab investigates the roles of spatial organization in biological processes and develops DNA nanotechnology-based tools to map and manipulate membrane protein
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addressed using in vitro biochemistry assays based on purified recombinant proteins, and/or through cell and molecular biology techniques in human cells. Qualifications The candidate should hold, or be about
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be based at the Department of Ecology and Environmental Science, Umeå University. The scholarship is funded by the Kempe Foundation and is on 360,000 SEK/year (tax-free). The postdoctoral fellow will