8 advance-soil-structure-modelling PhD positions at International PhD Programme (IPP) Mainz in Germany
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) are important mediators of most cellular processes. Understanding how proteins interact with each other, ideally at structural resolution, is key in understanding molecular processes, how disease mutations would
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aging in Cockayne syndrome (CS) patients. Chromatin serves as a platform for DNA repair and undergoes dynamic changes during the DNA damage response (DDR) through the Access-Repair-Restore model. Histones
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model systems zebrafish and fruit fly, and structural biology (including AlphaFold predictions and cryo-EM), we will dissect the roles of these novel mRNA export regulators and define how they interface
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or Th17 immune responses. Recent advances in single cell profiling have identified additional Dendritic cell populations, including transitional tDC and type 3 Dendritic cells. Yet, their functional role in
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as well as in aging mouse models. Identification of these interactions could provide new approaches to counteract or delay age associated exhaustion of HSC. PhD Project: Contribution of cellular
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, to how epigenetics regulates cellular identity or neural memory. Activities and responsibilities The research group of Petra Beli offers the following PhD project: R-loops are secondary DNA structures
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patterns and immunological outcomes. However, current interactome analyses have so far been limited to inferred interactions based on cellular receptor-ligand expression patterns. New technological advances
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environment, with English as our working language Advanced training in scientific techniques and professional skills Access to our state-of-the-art Core Facilities and their technical expertise Fully funded