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of reaction optimisation and synthesis of suitable reagents, test the conditions developed at the cellular level and purify and characterise (mass spectrometry) glycoRNA. The successful candidate will have (or
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synthetic biology and a thorough understanding of eukaryotic genomes and gene expression. Applicants should be proficient in the design and assembly of synthetic constructs, and in the use of mass
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-generation AI hardware (ASIC) accelerators. The UK's Advanced Research Invention Agency (ARIA) is supporting an ambitious programme of work that aims to reduce the the cost of AI by more than 1000x: https
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)-methylpseudouridylation of mRNA causes +1 ribosomal frameshifting. Nature 625, 189-194, doi:10.1038/s41586-023-06800-3 (2024). Van der Klaauw, A. A. et al. Accelerated waning of the humoral response to COVID-19 vaccines in