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to enhance regionalization and laminar organization within cortical-like structures. Through these studies, we seek to advance the development of a physiologically relevant human brain organoid model that more
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: (1) epigenetic analysis in a mouse models of Parkinson’s disease related exposures, (2) elucidating molecular mechanisms of pesticide-induced changes in DNA methylation in a 3D neurosphere model in
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. (2024). Programmed disassembly of a microtubule-based membrane protrusion network coordinates 3D epithelial morphogenesis in Drosophila. EMBO J. 43(4): 568-594. https://doi.org/10.1038/s44318-023-00025-w
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Responsibilities EE/CSE Makerspace: Assist students with their design projects (PCB design and milling, 3D modeling and printing, soldering, CNC mills, laser cutting). EE Labs: Trains students in effective use
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methodical, rigorous, reactive, and attentive, with a strong work ethic and high integrity. He/she will already have experience with human stem cells, neuronal differentiation, as well as 3D culture, organoids
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interdisciplinary projects of developing new cancer immunotherapy, using novel 3D tumor organoid models and 3D single-cell imaging. The incumbent(s) will learn cutting-edge techniques in immuno-oncology studies and
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. Contract The contract model to be used will be in follow the FCT scholarship holder contract draft available at the following link: https://ucppt-my.sharepoint.com/:w:/g/personal/ccabral_ucp_pt
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processes, multimodal data fusion, physics–ML hybrid modelling (from CFD to atomistic simulations), and AI-assisted hypothesis formulation. MSCA Doctoral Candidate eligibility criteria Applicants must comply
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. To overcome these limitations, the TUNIC project will utilize a “phenotype-first” approach. This involves: Creating a 3D “tumor-on-a-chip” (ToC) model: This model will incorporate primary human cells
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Instituto de Investigação e Inovação em Saúde da Universidade do Porto (i3S) | Portugal | 4 days ago
the outcome of pneumococcal infection. Using an innovative and multidisciplinary approach combining advanced light and electron microscopy, molecular cell biology, proteomics, 3D lung models and in vivo