PhD Position in Organic Synthesis and Chemical Biology

Updated: 2 months ago
Location: Dublin Bar, LEINSTER
Job Type: FullTime
Deadline: 31 May 2026

9 Feb 2026
Job Information
Organisation/Company

Trinity College Dublin
Department

School of Chemistry
Research Field

Chemistry » Organic chemistry
Chemistry » Molecular chemistry
Researcher Profile

First Stage Researcher (R1)
Positions

PhD Positions
Application Deadline

31 May 2026 - 22:00 (Europe/Dublin)
Country

Ireland
Type of Contract

Temporary
Job Status

Full-time
Hours Per Week

38
Offer Starting Date

1 Sep 2026
Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme
Is the Job related to staff position within a Research Infrastructure?

No

Offer Description

Marine algae sequester vast amounts of carbon in the ocean, yet the molecular mechanisms that allow this carbon to be stored for centuries remain poorly understood. This PhD project asks a fundamental question with global relevance: how does glycan structure control carbon sequestration in marine systems? 

By combining organic synthesis and chemical biology, the project aims to uncover the molecular features of marine polysaccharides that underpin this process.

Project Description

Marine algae produce complex polysaccharides (glycans) that play a poorly understood but potentially critical role in long-term carbon sequestration. This PhD project will use chemical synthesis and chemical biology to decode the molecular structures responsible for these properties.

This project will combine organic synthesis and chemical biology to:

  • Synthesise defined oligosaccharides and chemical probes using organic synthesis
  • Use chemical probes to investigate glycan carbon cycling in marine microbiomes
  • Explore the biological and potential medical properties of algal glycans

Working at the interface of organic synthesis and chemical biology, the successful candidate will investigate how specific glycans sequester carbon. The project is in a rapidly expanding research area, offering opportunities to publish and collaborate internationally and carry out your PhD in the TCD School of Chemistry, within the Trinity Biomedical Sciences Institute (TBSI).


Where to apply
E-mail

conor.crawford@tcd.ie

Requirements
Research Field
Chemistry
Education Level
Master Degree or equivalent

Research Field
Chemistry
Education Level
Bachelor Degree or equivalent

Skills/Qualifications

Candidate Profile

The ideal candidate will:

  • Hold a Bachelor’s or Master’s degree in chemistry, chemical biology, or a related discipline
  • Have experience and a strong interest in organic synthesis, carbohydrate chemistry, and/or chemical biology
  • Demonstrate analytical skills in the laboratory
  • Be curious, motivated, and enthusiastic about interdisciplinary research

Enthusiasm and willingness to learn new techniques are more important than existing specialisation in the glycosciences.


Languages
ENGLISH
Level
Excellent

Research Field
Chemistry » Organic chemistryChemistry » Molecular chemistry
Years of Research Experience
1 - 4

Internal Application form(s) needed
PhD_Crawford_2026.pdf
English
(289.1 KB - PDF)
Download
Additional Information
Website for additional job details

https://www.crawford-lab.eu/

Work Location(s)
Number of offers available
1
Company/Institute
School of Chemistry, Trinity Biomedical Sciences Institute, Trinity College Dublin
Country
Ireland
City
Dublin
Postal Code
D02 R590
Street
152-160 Pearse St
Geofield


Contact
City

Dublin
Website

https://www.crawford-lab.eu/
https://chemistry.tcd.ie/
Street

152 Pearse St
E-Mail

conor.crawford@tcd.ie

STATUS: EXPIRED

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