14 Feb 2026
Job Information
- Organisation/Company
Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences- Research Field
Chemistry » Inorganic chemistry- Researcher Profile
First Stage Researcher (R1)- Application Deadline
3 Mar 2026 - 22:50 (UTC)- Country
Czech Republic- Type of Contract
Temporary- Job Status
Full-time- Offer Starting Date
1 Oct 2026- Is the job funded through the EU Research Framework Programme?
Not funded by a EU programme- Is the Job related to staff position within a Research Infrastructure?
No
Offer Description
The aim of the thesis will be to synthesize PROTACs for several kinases, which are validated targets in oncology and in CNS disorders. It will be focused on linker optimization, selection of ligase ligands and specificity for target kinase. Our recently developed highly selective small molecule heterocyclic kinase inhibitors will serve as a starting point.
University: Faculty of Chemical Technology, UCT Prague; Faculty of Science, Charles University
Group: Michal Hocek Group / Bioorganic and Medicinal Chemistry of Nucleic Acids
Tutor: Prof. Ing. Michal Hocek, Ph.D. DSc.
Field of study: Organic chemistry
Apply: https://www.uochb.cz/en/call-for-phd-applications
Where to apply
- Website
- https://www.uochb.cz/en/call-for-phd-applications
Requirements
- Languages
- ENGLISH
- Level
- Good
Additional Information
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences
- Country
- Czech Republic
- City
- Praha 6
- Postal Code
- 160 00
- Street
- Flemingovo náměstí 542/2
STATUS: EXPIRED
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