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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 2 months ago
the design and enzymatic synthesis of hypermodified xeno-nucleic acids with a combination of modifications at the base, sugar moiety and phosphate linkages. After optimization of the methodology, hypermodified
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Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences | Czech | 2 months ago
PROTACs for several kinases, which are validated targets in oncology and in CNS disorders. It will be focused on linker optimization, selection of ligase ligands and specificity for target kinase. Our
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