Mapping Responses in Complex Microbial Systems using Advanced Measurements

NIST, United States

Updated: about 22 hours ago
Location: Gaithersburg, MARYLAND

RAP opportunity at National Institute of Standards and Technology     NIST

Mapping Responses in Complex Microbial Systems using Advanced Measurements


Location

Material Measurement Laboratory, Biosystems and Biomaterials Division


opportunity location
50.64.41.B8452 Gaithersburg, MD

NIST only participates in the February and August reviews.


Advisers
name email phone
Charles Henry Camp charles.camp@nist.gov 404.483.9588
Joy P. Dunkers joy.dunkers@nist.gov 301.975.6841
Young Jong Lee youngjong.lee@nist.gov 301.975.6832
Description

Quantifying composition and function of complex microbial systems is key to progress in understanding the important role that bacteria play in human health, from the gut microbiome to the global problem of anti-microbial resistance. Traditional microbial characterization approaches are often destructive, insufficient in resolution and sensitivity, and are subject to bias inherent in the measurement process. New methods for quantitative, in situ characterization are essential for gaining insight into microbial communities in their unperturbed state.

This project will use in situ advanced measurement techniques such as flow cytometry, quantum cascade laser infrared (QCL-IR) microscopy, and fluorescence microscopies, to obtain quantitative characterization of bacteria identity and location, metabolic state, and signaling molecules in commercially and clinically relevant mixed microbial communities and biofilms and compare the findings to traditional microbial analytical tools.


key words

Bacteria; biofilm; fluorescence; imaging; infrared; microbe; microbial; microbial community; microbiology; microbiome; microscopy; nanoculture


Eligibility

citizenship

Open to U.S. citizens


level

Open to Postdoctoral applicants


Stipend
Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00

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