Postdoctoral fellow (project leader)

University of Basel, Switzerland

Updated: about 1 month ago

The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need.

With more than 70 research groups and 800 employees, the Department of Biomedicine is the largest department at the University. We are located in the heart of Basel at 6 different locations. Be part of our future!
Antibiotic testing is still defined by bulk growth inhibition measurements. We aim to replace this paradigm by quantifying antibiotic action at single-cell resolution.

The scientific aim

Our laboratory has established a large-scale live-cell imaging platform that tracks hundreds of millions of individual bacteria during antibiotic exposure (Nature Microbiology, 2026). This platform enables systematic assessments of tens of thousands of experimental conditions across bacterial species, clinical strains and diverse drug treatments. These experiments capture antibiotic activity in real-time at the level of individual cells. Yet much of the biological information embedded in these data remains unexplored. The next step is to convert these time-lapse images into accurate single-cell trajectories and subsequently into models of antibiotic responses, with direct relevance for drug development and patient treatment. We (boecklab.com) are looking for a scientist who will define the computational backbone of this programme.


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