Immobilized and co-immobilized whole-cell biocatalysts for enzyme cascade reactions

Organisation/Company

Chemický ústav SAV / Institute of Chemistry SAS

Research Field

Chemistry

Researcher Profile

First Stage Researcher (R1)

Positions

PhD Positions

Application Deadline

31 May 2026 - 23:59 (Europe/Bratislava)

Country

Slovakia

Type of Contract

Temporary

Job Status

Full-time

Is the job funded through the EU Research Framework Programme?

Not funded by a EU programme

Is the Job related to staff position within a Research Infrastructure?

No

The aim of the dissertation will be the research and development of innovative immobilized and co-immobilized whole-cell biocatalysts based on viable recombinant E. coli cells for the production of chemical specialties. The cascade of three redox enzymes co-expressed in E. coli bacteria as well as recombinant cells with produced Baeyer-Villiger monooxygenases will be stabilized using innovative immobilization and co-immobilization methods of entrapment and encapsulation. Hydrogel and polyelectrolyte particles and capsules prepared using sophisticated, powerful devices will be used as immobilization matrices. The productivity and stability of immobilized biocatalysts will be tested in parallel controlled bioreactors. The characterization of their key biocatalytic parameters will be carried out using the most modern techniques in cooperation with top domestic and foreign laboratories.

E-mail

chembuck@savba.sk

Research Field

Chemistry

Education Level

Master Degree or equivalent

Number of offers available

1

Company/Institute

Chemický ústav SAV / Institute of Chemistry SAS

Country

Slovakia

Geofield

City

Bratislava

Website

https://www.savba.sk

Street

Dúbravská cesta 5807/9

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