Doctoral researcher in Translational Neuroscience

University of Luxembourg, Luxembourg

Updated: about 1 month ago
Deadline: ;

The University of Luxembourg is an international research university with a distinctly multilingual and interdisciplinary character.

The Faculty of Science, Technology and Medicine (FSTM) at the University of Luxembourg contributes multidisciplinary expertise in the fields of Mathematics, Physics, Engineering, Computer Science, Life Sciences and Medicine. Through its dual mission of teaching and research, the FSTM seeks to generate and disseminate knowledge and train new generations of responsible citizens in order to better understand, explain and advance society and environment we live in.

We are looking for a highly motivated and dynamic PhD student for a position in the Translational Neuroscience team headed by Prof. Rejko KRÜGER.

The Translational Neuroscience team's focus lies in the identification of new biomarkers and therapeutic targets for Parkinson’s disease, aimed at bridging the gap between fundamental research and clinical research by embedding the “bed to bench to bedside” research approach. Fundamental research focuses on induced pluripotent stem cell (iPSC)-derived neuronal models to elucidate the molecular and cellular alterations contributing to neurodegeneration in familial and idiopathic forms of PD, Dementia with Lewy bodies, atypical parkinsonism, e.g. PSP or MSA, and REM sleep behaviour disorder (RBD).

Newly discovered molecular targets and disease-associated cellular phenotypes are used as readouts in drug screening approaches, to identify molecules that, after in vitro and in vivo validation, could be potentially used in future intelligent clinical trials. The clinical research focus is part of the National Centre for Excellence in Research on Parkinson’s Disease (NCER-PD ), an initiative originally funded by the Luxembourg National Research Fund.


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