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, the causative agent of cholera. We perform detailed studies using specimens derived from human samples. Projects include: Creating knock-out mutants to study how V. cholerae virulence is impacted by gut bacteria
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to conduct clinical research with human eye specimens. Our work spans three major directions: * Basic Research: we investigate the cellular and molecular mechanisms of ocular tissue development and homeostasis
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channels modulates these pathways. We use mouse models and primary human cells to query immune function in vitro and in vivo. Core experimental techniques include mouse disease models, in vitro functional
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Position Summary The Ushiki Lab investigates the molecular mechanisms of cis-regulatory function and how noncoding genetic variation alters gene regulation in human disease. Our work integrates
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infection. We focus on defining host pathways that can be therapeutically leveraged to target the HIV reservoir. Our work integrates molecular virology, primary human cell systems, and in vivo models. We
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. * Human translational validation using the VDAART randomized clinical trial cohort (prenatal vitamin D supplementation, childhood cardiometabolic outcomes, methylation arrays). * Developmental programming
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progression. These projects utilize a wide breadth of technologies from single cell sequencing to mass spectrometry to high throughput, quantitative imaging. In addition, we use human genetics, AAV viral
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, and human samples. The lab has successfully competed for various funding. The appointment is viewed as a training or transitional period preparatory to an academic, industrial, governmental, or other
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, Data science, Statistical Genomics or a related discipline involving the interrogation of ‘omics’ datasets. Hands-on experience with large-scale human omics (preferably related to neurodegeneration
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interdisciplinary lab group investigating tendon injury and healing. Current projects within the lab span from human subjects research to the study of ex vivo tissues and preclinical models. This position is